Scientists have been studying free radicals and oxidative stress and its effects for many years. Studies in this area have increased in the last decades and, currently, the association between oxidative stress and diseases such as cancer, atherosclerosis, fibromyalgia, and autoimmune disorders, in addition to aging-related processes, is well-established in humans. In dogs and cats, studies on these associations are recent and show how oxidative stress affects pets’ health and is associated with specific diseases such as obesity, renal failure, central nervous diseases, and cognitive functions — to mention a few.
The consequences of oxidative stress are multiple. At the cellular level, the most harmful effect of oxidative stress is represented by lipid peroxidation of the cell membranes, which invariably leads to alterations in the cell’s structure and permeability. Of course, the physiological status of the animal is affected by molecular and cellular damage. The health of an animal is therefore affected by a compromised immune status.
As mentioned, damage attributable to oxidative stress is recognized as a prominent feature in numerous disease processes.
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